Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal developme...
Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Mouse sex determination provides an attractive model to study how regulatory genetic networks and signaling pathways control cell specification and cell fate decisions. This study characterizes in detail the essential role played by the insulin receptor (INSR) and the IGF type I receptor (IGF1R) in adrenogenital development and primary sex determin...
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Full title
Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice
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TN_cdi_plos_journals_1314342053
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1314342053
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1003160
