Ligand-induced modulation of the free-energy landscape of G protein-coupled receptors explored by ad...
Ligand-induced modulation of the free-energy landscape of G protein-coupled receptors explored by adaptive biasing techniques
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Extensive experimental information supports the formation of ligand-specific conformations of G protein-coupled receptors (GPCRs) as a possible molecular basis for their functional selectivity for signaling pathways. Taking advantage of the recently published inactive and active crystal structures of GPCRs, we have implemented an all-atom computati...
Alternative Titles
Full title
Ligand-induced modulation of the free-energy landscape of G protein-coupled receptors explored by adaptive biasing techniques
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1314501680
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1314501680
Other Identifiers
ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1002193
