Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mut...
Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The HERC gene family encodes proteins with two characteristic domains: HECT and RCC1-like. Proteins with HECT domains have been described to function as ubiquitin ligases, and those that contain RCC1-like domains have been reported to function as GTPases regulators. These two activities are essential in a number of important cellular processes such...
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Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase
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TN_cdi_plos_journals_1314510927
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1314510927
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000784
