Infected Cell Killing by HIV-1 Protease Promotes NF-κB Dependent HIV-1 Replication
Infected Cell Killing by HIV-1 Protease Promotes NF-κB Dependent HIV-1 Replication
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Publisher
San Francisco: Public Library of Science
Journal title
Language
English
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Publisher
San Francisco: Public Library of Science
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Scope and Contents
Contents
Acute HIV-1 infection of CD4 T cells often results in apoptotic death of infected cells, yet it is unclear what evolutionary advantage this offers to HIV-1. Given the independent observations that acute T cell HIV-1 infection results in (1) NF-κB activation, (2) caspase 8 dependent apoptosis, and that (3) caspase 8 directly activates NF-κB, we ques...
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Full title
Infected Cell Killing by HIV-1 Protease Promotes NF-κB Dependent HIV-1 Replication
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TN_cdi_plos_journals_1318799545
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1318799545
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0002112
