Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells
Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
NK cells have therapeutic potential for a wide variety of human malignancies. However, because NK cells expand poorly in vitro, have limited life spans in vivo, and represent a small fraction of peripheral white blood cells, obtaining sufficient cell numbers is the major obstacle for NK-cell immunotherapy. Genetically-engineered artificial antigen-...
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Full title
Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells
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TN_cdi_plos_journals_1323091202
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323091202
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0030264
