Novel AlkB dioxygenases--alternative models for in silico and in vivo studies
Novel AlkB dioxygenases--alternative models for in silico and in vivo studies
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly contributing to tumor formation and used in cancer therapy. In silico analysis and in vivo studies have shown...
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Full title
Novel AlkB dioxygenases--alternative models for in silico and in vivo studies
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TN_cdi_plos_journals_1323432899
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323432899
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0030588
