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Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptot...

Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptot...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324449035

Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death

About this item

Full title

Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-04, Vol.7 (4), p.e34929-e34929

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Mitochondria are best known as the essential intracellular organelles that host the homeostasis required for cellular survival, but they also have relevance in diverse disease-related conditions, including Alzheimer's disease (AD). Amyloid β (Aβ) peptide is the key molecule in AD pathogenesis, and has been highlighted in the implication of mitochon...

Alternative Titles

Full title

Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1324449035

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324449035

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0034929

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