Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation
Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Epigenetic silencing is one of the mechanisms leading to inactivation of a tumor suppressor gene, either by DNA methylation or histone modification in a promoter regulatory region. Mitogen inducible gene 6 (MIG-6), mainly known as a negative feedback inhibitor of the epidermal growth factor receptor (EGFR) family, is a tumor suppressor gene that is...
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Full title
Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation
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TN_cdi_plos_journals_1325027687
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325027687
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0038955
