Astragaloside IV, a novel antioxidant, prevents glucose-induced podocyte apoptosis in vitro and in v...
Astragaloside IV, a novel antioxidant, prevents glucose-induced podocyte apoptosis in vitro and in vivo
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Glucose-induced reactive oxygen species (ROS) production initiates podocyte apoptosis, which represents a novel early mechanism leading to diabetic nephropathy (DN). Here, we tested the hypothesis that Astragaloside IV(AS-IV) exerts antioxidant and antiapoptotic effects on podocytes under diabetic conditions. Apoptosis, albuminuria, ROS generation,...
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Full title
Astragaloside IV, a novel antioxidant, prevents glucose-induced podocyte apoptosis in vitro and in vivo
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TN_cdi_plos_journals_1325029173
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325029173
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0039824
