Protective roles of DMP1 in high phosphate homeostasis
Protective roles of DMP1 in high phosphate homeostasis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Dmp1 (dentin matrix protein1) null mice (Dmp1(-/-)) display hypophosphatemic rickets with a sharp increase in fibroblast growth factor 23 (FGF23). Disruption of Klotho (the obligatory co-receptor of FGF23) results in hyperphosphatemia with ectopic calcifications formed in blood vessels and kidneys. To determine the role of DMP1 in both a hyperphosp...
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Full title
Protective roles of DMP1 in high phosphate homeostasis
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TN_cdi_plos_journals_1326223139
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326223139
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0042329
