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Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and...

Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326223612

Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma

About this item

Full title

Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-07, Vol.7 (7), p.e41036-e41036

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Epigenetic modification of DNA by cytosine methylation to produce 5-methylcytosine (5mC) has become well-recognized as an important epigenetic process in human health and disease. Recently, further modification of 5mC by the ten eleven translocated (TET) family of enzymes to produce 5-hydroxymethylcytosine (5hmC) has been described. In the present...

Alternative Titles

Full title

Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326223612

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326223612

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0041036

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