Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier
Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Placental P-glycoprotein (P-gp) acts to protect the developing fetus from exogenous compounds. This protection declines with advancing gestation leaving the fetus and fetal brain vulnerable to these compounds and potential teratogens in maternal circulation. This vulnerability may be more pronounced in pregnancies complicated by infection, which is...
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Full title
Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier
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TN_cdi_plos_journals_1326238547
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326238547
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0043022