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Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier

Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326238547

Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier

About this item

Full title

Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-08, Vol.7 (8), p.e43022

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Placental P-glycoprotein (P-gp) acts to protect the developing fetus from exogenous compounds. This protection declines with advancing gestation leaving the fetus and fetal brain vulnerable to these compounds and potential teratogens in maternal circulation. This vulnerability may be more pronounced in pregnancies complicated by infection, which is...

Alternative Titles

Full title

Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326238547

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326238547

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0043022

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