Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer
Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The CD44 transmembrane glycoproteins play multifaceted roles in tumor progression and metastasis. CD44 expression has also been associated with stem-like breast cancer cells. Hypoxia commonly occurs in tumors and is a major cause of radiation and chemo-resistance. Hypoxia is known to inhibit differentiation and facilitates invasion and metastasis....
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Full title
Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer
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Record Identifier
TN_cdi_plos_journals_1326542866
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326542866
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0044078
