Using FLIM-FRET to measure conformational changes of transglutaminase type 2 in live cells
Using FLIM-FRET to measure conformational changes of transglutaminase type 2 in live cells
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Transglutaminase type 2 (TG2) is a ubiquitously expressed member of the transglutaminase family, capable of mediating a transamidation reaction between a variety of protein substrates. TG2 also has a unique role as a G-protein with GTPase activity. In response to GDP/GTP binding and increases in intracellular calcium levels, TG2 can undergo a large...
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Full title
Using FLIM-FRET to measure conformational changes of transglutaminase type 2 in live cells
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TN_cdi_plos_journals_1326543390
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326543390
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0044159
