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SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular...

SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326544754

SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas

About this item

Full title

SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-09, Vol.7 (9), p.e45119

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The increased expression of SIRT1 has recently been identified in numerous human tumors and a possible correlation with c-Myc oncogene has been proposed. However, it remains unclear whether SIRT1 functions as an oncogene or tumor suppressor. We sought to elucidate the role of SIRT1 in liver cancer under the influence of c-Myc and to determine the p...

Alternative Titles

Full title

SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326544754

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326544754

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0045119

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