Mechanistic insights into validoxylamine A 7'-phosphate synthesis by VldE using the structure of the...
Mechanistic insights into validoxylamine A 7'-phosphate synthesis by VldE using the structure of the entire product complex
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The pseudo-glycosyltransferase VldE catalyzes non-glycosidic C-N coupling between an unsaturated cyclitol and a saturated aminocyclitol with the conservation of the stereochemical configuration of the substrates to form validoxylamine A 7'-phosphate, the biosynthetic precursor of the antibiotic validamycin A. To study the molecular basis of its mec...
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Full title
Mechanistic insights into validoxylamine A 7'-phosphate synthesis by VldE using the structure of the entire product complex
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TN_cdi_plos_journals_1326544962
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326544962
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0044934
