Low-dose oral sirolimus and the risk of menstrual-cycle disturbances and ovarian cysts: analysis of...
Low-dose oral sirolimus and the risk of menstrual-cycle disturbances and ovarian cysts: analysis of the randomized controlled SUISSE ADPKD trial
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Sirolimus has been approved for clinical use in non proliferative and proliferative disorders. It inhibits the mammalian target of rapamycin (mTOR) signaling pathway which is also known to regulate ovarian morphology and function. Preliminary observational data suggest the potential for ovarian toxicity but this issue has not been studied in random...
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Full title
Low-dose oral sirolimus and the risk of menstrual-cycle disturbances and ovarian cysts: analysis of the randomized controlled SUISSE ADPKD trial
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TN_cdi_plos_journals_1326551449
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326551449
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0045868
