TRIP Database 2.0: A Manually Curated Information Hub for Accessing TRP Channel Interaction Network
TRIP Database 2.0: A Manually Curated Information Hub for Accessing TRP Channel Interaction Network
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Transient receptor potential (TRP) channels are a family of Ca(2+)-permeable cation channels that play a crucial role in biological and disease processes. To advance TRP channel research, we previously created the TRIP (TRansient receptor potential channel-Interacting Protein) Database, a manually curated database that compiles scattered information on TRP channel protein-protein interactions (PPIs). However, the database needs to be improved for information accessibility and data utilization. Here, we present the TRIP Database 2.0 (http://www.trpchannel.org) in which many helpful, user-friendly web interfaces have been developed to facilitate knowledge acquisition and inspire new approaches to studying TRP channel functions: 1) the PPI information found in the supplementary data of referred articles was curated; 2) the PPI summary matrix enables users to intuitively grasp overall PPI information;...
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TRIP Database 2.0: A Manually Curated Information Hub for Accessing TRP Channel Interaction Network
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TN_cdi_plos_journals_1326558514
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326558514
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0047165
