High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signa...
High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway
About this item
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Author / Creator
Kim, Kyung-Ah , Gu, Wan , Lee, In-Ah , Joh, Eun-Ha and Kim, Dong-Hyun
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
While it is widely accepted that obesity is associated with low-grade systemic inflammation, the molecular origin of the inflammation remains unknown. Here, we investigated the effect of endotoxin-induced inflammation via TLR4 signaling pathway at both systemic and intestinal levels in response to a high-fat diet.
C57BL/6J and TLR4-deficient C57...
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Full title
High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway
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Author / Creator
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Record Identifier
TN_cdi_plos_journals_1326560418
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326560418
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0047713
