Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and am...
Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Different transmissible spongiform encephalopathy (TSE)-associated forms of prion protein (e.g. PrP(Sc)) can vary markedly in ultrastructure and biochemical characteristics, but each is propagated in the host. PrP(Sc) propagation involves conversion from its normal isoform, PrP(C), by a seeded or templated polymerization mechanism. Such a mechanism...
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Full title
Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC
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TN_cdi_plos_journals_1326737240
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326737240
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0048969
