Identification of small molecule inhibitors of PTPσ through an integrative virtual and biochemical a...
Identification of small molecule inhibitors of PTPσ through an integrative virtual and biochemical approach
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
PTPσ is a dual-domain receptor type protein tyrosine phosphatase (PTP) with physiologically important functions which render this enzyme an attractive biological target. Specifically, loss of PTPσ has been shown to elicit a number of cellular phenotypes including enhanced nerve regeneration following spinal cord injury (SCI), chemoresistance in cul...
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Full title
Identification of small molecule inhibitors of PTPσ through an integrative virtual and biochemical approach
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TN_cdi_plos_journals_1326746284
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326746284
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0050217
