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Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and e...

Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and e...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327124346

Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and enhance the killing of mycobacteria in macrophages

About this item

Full title

Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and enhance the killing of mycobacteria in macrophages

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-12, Vol.7 (12), p.e50345-e50345

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Pathogenic mycobacteria reside in, and are in turn controlled by, macrophages. However, emerging data suggest that neutrophils also play a critical role in innate immunity to tuberculosis, presumably by their different antibacterial granule proteins. In this study, we purified neutrophil azurophil and specific granules and systematically analyzed t...

Alternative Titles

Full title

Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and enhance the killing of mycobacteria in macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1327124346

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327124346

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0050345

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