SLC22A1-ABCB1 haplotype profiles predict imatinib pharmacokinetics in Asian patients with chronic my...
SLC22A1-ABCB1 haplotype profiles predict imatinib pharmacokinetics in Asian patients with chronic myeloid leukemia
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United States: Public Library of Science
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English
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United States: Public Library of Science
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This study aimed to explore the influence of SLC22A1, PXR, ABCG2, ABCB1 and CYP3A5 3 genetic polymorphisms on imatinib mesylate (IM) pharmacokinetics in Asian patients with chronic myeloid leukemia (CML).
Healthy subjects belonging to three Asian populations (Chinese, Malay, Indian; n = 70 each) and CML patients (n = 38) were enrolled in a prosp...
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SLC22A1-ABCB1 haplotype profiles predict imatinib pharmacokinetics in Asian patients with chronic myeloid leukemia
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TN_cdi_plos_journals_1327188158
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327188158
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0051771
