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Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of...

Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327225086

Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of protein tyrosine phosphatase CD45

About this item

Full title

Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of protein tyrosine phosphatase CD45

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-12, Vol.7 (12), p.e52495

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Hydrogen peroxide induces oxidation and consequently inactivation of many protein tyrosine phosphatases. It was found that hydrogen peroxide, in the presence of carboxylic acids, was efficiently activated to form even more potent oxidant - peroxy acid. We have found that peroxytetradecanoic acid decreases the enzymatic activity of CD45 phosphatase...

Alternative Titles

Full title

Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of protein tyrosine phosphatase CD45

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1327225086

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327225086

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0052495

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