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Extended and structurally supported insights into extracellular hormone binding, signal transduction...

Extended and structurally supported insights into extracellular hormone binding, signal transduction...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327230980

Extended and structurally supported insights into extracellular hormone binding, signal transduction and organization of the thyrotropin receptor

About this item

Full title

Extended and structurally supported insights into extracellular hormone binding, signal transduction and organization of the thyrotropin receptor

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-12, Vol.7 (12), p.e52920-e52920

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The hormone thyrotropin (TSH) and its receptor (TSHR) are crucial for the growth and function of the thyroid gland. The TSHR is evolutionary linked with the receptors of follitropin (FSHR) and lutropin/choriogonadotropin (LHR) and their sequences and structures are similar. The extracellular region of TSHR contains more than 350 amino acids and bin...

Alternative Titles

Full title

Extended and structurally supported insights into extracellular hormone binding, signal transduction and organization of the thyrotropin receptor

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1327230980

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327230980

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0052920

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