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Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TL...

Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TL...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327255751

Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner

About this item

Full title

Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-01, Vol.8 (1), p.e54040-e54040

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Opiates are among the most prescribed drugs for pain management. However, morphine use or abuse results in significant gut bacterial translocation and predisposes patients to serious infections with gut origin. The mechanism underlying this defect is still unknown. In this report, we investigated the mechanisms underlying compromised gut immune fun...

Alternative Titles

Full title

Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1327255751

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327255751

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0054040

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