Fine characterisation of a recombination hotspot at the DPY19L2 locus and resolution of the paradoxi...
Fine characterisation of a recombination hotspot at the DPY19L2 locus and resolution of the paradoxical excess of duplications over deletions in the general population
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United States: Public Library of Science
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English
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United States: Public Library of Science
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We demonstrated previously that 75% of infertile men with round, acrosomeless spermatozoa (globozoospermia) had a homozygous 200-Kb deletion removing the totality of DPY19L2. We showed that this deletion occurred by Non-Allelic Homologous Recombination (NAHR) between two homologous 28-Kb Low Copy Repeats (LCRs) located on each side of the gene. The...
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Fine characterisation of a recombination hotspot at the DPY19L2 locus and resolution of the paradoxical excess of duplications over deletions in the general population
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TN_cdi_plos_journals_1327764004
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327764004
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1553-7404,1553-7390
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1553-7404
DOI
10.1371/journal.pgen.1003363
