A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and...
A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Infiltration of myeloid cells in the tumor microenvironment is often associated with enhanced angiogenesis and tumor progression, resulting in poor prognosis in many types of cancer. The polypeptide chemokine PK2 (Bv8, PROK2) has been shown to regulate myeloid cell mobilization from the bone marrow, leading to activation of the angiogenic process,...
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A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer
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TN_cdi_plos_journals_1327892808
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327892808
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0054916
