Early detection of abnormal prion protein in genetic human prion diseases now possible using real-ti...
Early detection of abnormal prion protein in genetic human prion diseases now possible using real-time QUIC assay
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The definitive diagnosis of genetic prion diseases (gPrD) requires pathological confirmation. To date, diagnosis has relied upon the finding of the biomarkers 14-3-3 protein and total tau (t-tau) protein in the cerebrospinal fluid (CSF), but many researchers have reported that these markers are not sufficiently elevated in gPrD, especially in Gerst...
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Full title
Early detection of abnormal prion protein in genetic human prion diseases now possible using real-time QUIC assay
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TN_cdi_plos_journals_1327892824
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327892824
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0054915
