Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice D...
Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner
About this item
Full title
Author / Creator
Borissoff, Julian I. , Otten, Jeroen J. T. , Heeneman, Sylvia , Leenders, Peter , van Oerle, René , Soehnlein, Oliver , Loubele, Sarah T. B. G. , Hamulyák, Karly , Hackeng, Tilman M. , Daemen, Mat J. A. P. , Degen, Jay L. , Weiler, Hartmut , Esmon, Charles T. , van Ryn, Joanne , Biessen, Erik A. L. , Spronk, Henri M. H. and ten Cate, Hugo
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Variations in the blood coagulation activity, determined genetically or by medication, may alter atherosclerotic plaque progression, by influencing pleiotropic effects of coagulation proteases. Published experimental studies have yielded contradictory findings on the role of hypercoagulability in atherogenesis. We therefore sought to address this m...
Alternative Titles
Full title
Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner
Authors, Artists and Contributors
Author / Creator
Otten, Jeroen J. T.
Heeneman, Sylvia
Leenders, Peter
van Oerle, René
Soehnlein, Oliver
Loubele, Sarah T. B. G.
Hamulyák, Karly
Hackeng, Tilman M.
Daemen, Mat J. A. P.
Degen, Jay L.
Weiler, Hartmut
Esmon, Charles T.
van Ryn, Joanne
Biessen, Erik A. L.
Spronk, Henri M. H.
ten Cate, Hugo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1330877255
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330877255
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0055784
