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23 results for van+Ryn,+Joanne

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Newsletter articlesFull Text
Van Ryn Joanne, Clemens Andreas and Boehringer Ingelheim International GmbH Apply for Patent on Dabigatran in Tumor Therapy
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2014
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Newsletter articlesFull Text
U.S. Patent and Trademark Office Receives Van Ryn Joanne, Hilberg Frank, Garin-Chesa Pilar and Boehringer Ingelheim International GmbH's Patent Application for Combination Therapy in Treatment of Onco...
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2014
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ArticlesPeer ReviewedFull Text
Idarucizumab, A specific reversal agent for dabigatran: Mode of action, pharmacokinetics and pharmacodynamics, and safety and efficacy in phase 1 subjects
Author / Creator:Reilly, Paul A., PhD ; van Ryn, Joanne, PhD ; Grottke, Oliver, MD, PhD ; Glund, Stephan, PhD ; Stangier, Joachim, PhD
Publisher:United States: Elsevier Inc
Journal title:The American journal of emergency medicine, 2016-11, Vol.34 (11), p.26-32
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ArticlesPeer ReviewedFull Text
Idarucizumab for Dabigatran Reversal — Full Cohort Analysis
Author / Creator:Pollack, Charles V ; Reilly, Paul A ; van Ryn, Joanne ; Eikelboom, John W ; Glund, Stephan ; Bernstein, Richard A ; Dubiel, Robert ; Huisman, Menno V ; Hylek, Elaine M ; Kam, Chak-Wah ; Kamphuisen, Pieter W ; Kreuzer, Jörg ; Levy, Jerrold H ; Royle, Gordon ; Sellke, Frank W ; Stangier, Joachim ; Steiner, Thorsten ; Verhamme, Peter ; Wang, Bushi ; Young, Laura ; Weitz, Jeffrey I
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-08, Vol.377 (5), p.431-441
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ArticlesPeer ReviewedFull Text
Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial
Author / Creator:Glund, Stephan, Dr ; Stangier, Joachim, PhD ; Schmohl, Michael, PhD ; Gansser, Dietmar, PhD ; Norris, Stephen, PhD ; van Ryn, Joanne, PhD ; Lang, Benjamin, Dipl Math oec ; Ramael, Steven, MD ; Moschetti, Viktoria, MD ; Gruenenfelder, Fredrik, DVM ; Reilly, Paul, PhD ; Kreuzer, Jörg, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2015-08, Vol.386 (9994), p.680-690
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ArticlesPeer ReviewedFull Text
Thrombin promotes diet-induced obesity through fibrin-driven inflammation
Author / Creator:Kopec, Anna K. ; Abrahams, Sara R. ; Thornton, Sherry ; Palumbo, Joseph S. ; Mullins, Eric S. ; Divanovic, Senad ; Weiler, Hartmut ; Owens, A. Phillip ; Mackman, Nigel ; Goss, Ashley ; van Ryn, Joanne ; Luyendyk, James P. ; Flick, Matthew J.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-08, Vol.127 (8), p.3152-3166
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ArticlesPeer ReviewedFull Text
Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model
Author / Creator:Grottke, Oliver ; van Ryn, Joanne ; Spronk, Henri MH ; Rossaint, Rolf
Publisher:England: BioMed Central
Journal title:Critical care (London, England), 2014-02, Vol.18 (1), p.R27-R27, Article R27
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ArticlesPeer ReviewedFull Text
Dabigatran etexilate retards the initiation and progression of atherosclerotic lesions and inhibits the expression of oncostatin M in apolipoprotein E-deficient mice
Author / Creator:Preusch, Michael R. ; Ieronimakis, Nicholas ; Wijelath, Errol S. ; Ricks, Jerry ; Bea, Florian ; Reyes, Morayma ; van Ryn, Joanne ; Rosenfeld, Michael E. ; Cabbage, Sara
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Drug design, development and therapy, 2015-01, Vol.9, p.5203-5211
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ArticlesPeer ReviewedFull Text
Comments on—Switching from vitamin K antagonist to dabigatran in atrial fibrillation: differences according to dose
Author / Creator:Heinrich-Nols, Jutta ; van Ryn, Joanne
Publisher:England: Oxford University Press
Journal title:European heart journal. Cardiovascular pharmacotherapy, 2021-01, Vol.7 (1), p.74-74
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ArticlesPeer ReviewedFull Text
The Renal Elimination Pathways of the Dabigatran Reversal Agent Idarucizumab and its Impact on Dabigatran Elimination
Author / Creator:Glund, Stephan ; Gan, Guanfa ; Moschetti, Viktoria ; Reilly, Paul ; Honickel, Markus ; Grottke, Oliver ; Van Ryn, Joanne
Publisher:Los Angeles, CA: SAGE Publications
Journal title:Clinical and applied thrombosis/hemostasis, 2018-07, Vol.24 (5), p.724-733
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ArticlesPeer ReviewedFull Text
Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution
Author / Creator:Grottke, Oliver ; van Ryn, Joanne ; Zentai, Christian ; Gan, Guanfa ; Honickel, Markus ; Rossaint, Rolf ; ten Cate, Hugo ; Spronk, Henri M. H.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-01, Vol.14 (1), p.e0209350-e0209350
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ArticlesPeer ReviewedFull Text
Switching from enoxaparin to dabigatran etexilate: pharmacokinetics, pharmacodynamics, and safety profile
Author / Creator:Clemens, Andreas ; van Ryn, Joanne ; Sennewald, Regina ; Yamamura, Norio ; Stangier, Joachim ; Feuring, Martin ; Härtter, Sebastian
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:European journal of clinical pharmacology, 2012-05, Vol.68 (5), p.607-616
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ArticlesPeer ReviewedFull Text
COX-2 Selectivity and Inflammatory Processes
Author / Creator:van Ryn, Joanne ; Trummlitz, Gnnter ; Pairet, Michel
Publisher:Schiphol: Bentham Science Publishers Ltd
Journal title:Current medicinal chemistry, 2000-11, Vol.7 (11), p.1145-1161
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ArticlesPeer ReviewedFull Text
Idarucizumab for Dabigatran Reversal — Full Cohort Analysis
Author / Creator:Pollack, Charles V. ; Reilly, Paul A. ; van Ryn, Joanne ; Eikelboom, John W. ; Glund, Stephan ; Bernstein, Richard A. ; Dubiel, Robert ; Huisman, Menno V. ; Hylek, Elaine M. ; Kam, Chak-Wah ; Kamphuisen, Pieter W. ; Kreuzer, Jörg ; Levy, Jerrold H. ; Royle, Gordon ; Sellke, Frank W. ; Stangier, Joachim ; Steiner, Thorsten ; Verhamme, Peter ; Wang, Bushi ; Young, Laura ; Weitz, Jeffrey I.
Journal title:The New England journal of medicine, 2017-08, Vol.377 (5), p.431-441
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ArticlesPeer ReviewedFull Text
Effect of Age and Renal Function on Idarucizumab Pharmacokinetics and Idarucizumab-Mediated Reversal of Dabigatran Anticoagulant Activity in a Randomized, Double-Blind, Crossover Phase Ib Study
Author / Creator:Glund, Stephan ; Stangier, Joachim ; van Ryn, Joanne ; Schmohl, Michael ; Moschetti, Viktoria ; Haazen, Wouter ; De Smet, Marina ; Gansser, Dietmar ; Norris, Stephen ; Lang, Benjamin ; Reilly, Paul ; Kreuzer, Jörg
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2017-01, Vol.56 (1), p.41-54
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ArticlesPeer ReviewedFull Text
COX-2 Blockade in Cancer Prevention and Therapy
Author / Creator:van Ryn, Joanne ; van Meel, Jacques
Publisher:New York: Springer Nature B.V
Journal title:Inflammation research, 2003-07, Vol.52 (8), p.311-312
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ArticlesPeer ReviewedFull Text
Authors’ Reply to Kamel et al.: “Effect of Age and Renal Function on Idarucizumab Pharmacokinetics and Idarucizumab-Mediated Reversal of Dabigatran Anticoagulant Activity in a Randomized, Double-Blind...
Author / Creator:Glund, Stephan ; Reilly, Paul ; van Ryn, Joanne ; Stangier, Joachim
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2017-02, Vol.56 (2), p.209-210
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ArticlesPeer ReviewedFull Text
Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner
Author / Creator:Borissoff, Julian I. ; Otten, Jeroen J. T. ; Heeneman, Sylvia ; Leenders, Peter ; van Oerle, René ; Soehnlein, Oliver ; Loubele, Sarah T. B. G. ; Hamulyák, Karly ; Hackeng, Tilman M. ; Daemen, Mat J. A. P. ; Degen, Jay L. ; Weiler, Hartmut ; Esmon, Charles T. ; van Ryn, Joanne ; Biessen, Erik A. L. ; Spronk, Henri M. H. ; ten Cate, Hugo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-02, Vol.8 (2), p.e55784-e55784
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ArticlesPeer ReviewedFull Text
Comment on: "Effect of Age and Renal Function on Idarucizumab Pharmacokinetics and Idarucizumab-Mediated Reversal of Dabigatran Anticoagulant Activity in a Randomized, Double-Blind, Crossover Phase Ib...
Author / Creator:Kamel, Kirollos S ; L Chin, Paul K ; Doogue, Matthew P ; Barclay, Murray L ; Glund, Stephan ; Reilly, Paul ; van Ryn, Joanne ; Stangier, Joachim
Publisher:Auckland: Springer Nature B.V
Journal title:Clinical pharmacokinetics, 2017-02, Vol.56 (2), p.207
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ArticlesPeer ReviewedFull Text
Translational Insights into Traumatic Brain Injury Occurring during Dabigatran or Warfarin Anticoagulation
Author / Creator:Schaefer, Jan Hendrik ; Leung, Wendy ; Wu, Limin ; Van Cott, Elizabeth M ; Lok, Josephine ; Whalen, Michael ; van Leyen, Klaus ; Lauer, Arne ; van Ryn, Joanne ; Lo, Eng H ; Foerch, Christian
Publisher:London, England: SAGE Publications
Journal title:Journal of cerebral blood flow and metabolism, 2014-05, Vol.34 (5), p.870-875
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Van Ryn Joanne, Clemens Andreas and Boehringer Ingelheim International GmbH Apply for Patent on Dabigatran in Tumor Therapy

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U.S. Patent and Trademark Office Receives Van Ryn Joanne, Hilberg Frank, Garin-Chesa Pilar and Boehringer Ingelheim International GmbH's Patent Application for Combination Therapy in Treatment of Onco...

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Idarucizumab, A specific reversal agent for dabigatran: Mode of action, pharmacokinetics and pharmacodynamics, and safety and efficacy in phase 1 subjects

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Idarucizumab for Dabigatran Reversal — Full Cohort Analysis

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Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial

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Thrombin promotes diet-induced obesity through fibrin-driven inflammation

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Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model

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Dabigatran etexilate retards the initiation and progression of atherosclerotic lesions and inhibits the expression of oncostatin M in apolipoprotein E-deficient mice

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Comments on—Switching from vitamin K antagonist to dabigatran in atrial fibrillation: differences according to dose

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The Renal Elimination Pathways of the Dabigatran Reversal Agent Idarucizumab and its Impact on Dabigatran Elimination

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Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution

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Switching from enoxaparin to dabigatran etexilate: pharmacokinetics, pharmacodynamics, and safety profile

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COX-2 Selectivity and Inflammatory Processes

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Idarucizumab for Dabigatran Reversal — Full Cohort Analysis

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Effect of Age and Renal Function on Idarucizumab Pharmacokinetics and Idarucizumab-Mediated Reversal of Dabigatran Anticoagulant Activity in a Randomized, Double-Blind, Crossover Phase Ib Study

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COX-2 Blockade in Cancer Prevention and Therapy

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Authors’ Reply to Kamel et al.: “Effect of Age and Renal Function on Idarucizumab Pharmacokinetics and Idarucizumab-Mediated Reversal of Dabigatran Anticoagulant Activity in a Randomized, Double-Blind...

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Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner

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Comment on: "Effect of Age and Renal Function on Idarucizumab Pharmacokinetics and Idarucizumab-Mediated Reversal of Dabigatran Anticoagulant Activity in a Randomized, Double-Blind, Crossover Phase Ib...

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Translational Insights into Traumatic Brain Injury Occurring during Dabigatran or Warfarin Anticoagulation

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