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Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a ce...

Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a ce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330880921

Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation

About this item

Full title

Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-02, Vol.8 (2), p.e54722

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Demyelination and axonal damage are critical processes in the pathogenesis of multiple sclerosis (MS). Oxidative stress and pro-inflammatory cytokines elicited by inflammation mediates tissue damage.
To monitor the demyelination and axonal injury associated with microglia activation we employed a model using cerebellar organotypic cultures stimu...

Alternative Titles

Full title

Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330880921

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330880921

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0054722

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