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Gli as a novel therapeutic target in malignant pleural mesothelioma

Gli as a novel therapeutic target in malignant pleural mesothelioma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330881488

Gli as a novel therapeutic target in malignant pleural mesothelioma

About this item

Full title

Gli as a novel therapeutic target in malignant pleural mesothelioma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-03, Vol.8 (3), p.e57346

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Malignant pleural mesothelioma (MPM) is a highly aggressive tumor with poor prognosis. Current treatment is rarely curative, thus novel meaningful therapies are urgently needed. Inhibition of Hedgehog (Hh) signaling at the cell membrane level in several cancers has shown anti-cancer activity in recent clinical studies. Evidence of Hh-independent Gl...

Alternative Titles

Full title

Gli as a novel therapeutic target in malignant pleural mesothelioma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330881488

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330881488

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0057346

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