Cysteine (C)-x-C receptor 4 undergoes transportin 1-dependent nuclear localization and remains funct...
Cysteine (C)-x-C receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cells
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The G-protein coupled receptor (GPCR), Cysteine (C)-X-C Receptor 4 (CXCR4), plays an important role in prostate cancer metastasis. CXCR4 is generally regarded as a plasma membrane receptor where it transmits signals that support transformation, progression and eventual metastasis. Due to the central role of CXCR4 in tumorigenesis, therapeutics appr...
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Full title
Cysteine (C)-x-C receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cells
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TN_cdi_plos_journals_1330881713
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330881713
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0057194
