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Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activati...

Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330882039

Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers

About this item

Full title

Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-02, Vol.8 (2), p.e56527

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Type-I interferon (IFN-I) has been increasingly implicated in HIV-1 pathogenesis. Various studies have shown elevated IFN-I and an IFN-I-induced gene and protein expression signature in HIV-1 infection, yet the elevated IFN-I species has not been conclusively identified, its source remains obscure and its role in driving HIV-1 pathogenesis is contr...

Alternative Titles

Full title

Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330882039

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330882039

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0056527

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