Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization...
Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Chronic inflammation-promoted metastasis has been considered as a major challenge in cancer therapy. Pro-inflammatory cytokine TNFα can induce cancer invasion and metastasis associated with epithelial-mesenchymal transition (EMT). However, the underlying mechanisms are not entirely clear. In this study, we showed that TNFα induces EMT in human HCT1...
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Full title
Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer
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TN_cdi_plos_journals_1330882282
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330882282
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0056664