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Autophagy inhibition promotes 5-fluorouraci-induced apoptosis by stimulating ROS formation in human...

Autophagy inhibition promotes 5-fluorouraci-induced apoptosis by stimulating ROS formation in human...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330882308

Autophagy inhibition promotes 5-fluorouraci-induced apoptosis by stimulating ROS formation in human non-small cell lung cancer A549 cells

About this item

Full title

Autophagy inhibition promotes 5-fluorouraci-induced apoptosis by stimulating ROS formation in human non-small cell lung cancer A549 cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-02, Vol.8 (2), p.e56679

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Chemotherapy is an important option for the treatment of various cancers including lung cancer. However, tumor resistance towards cytotoxic chemotherapy has become more common. It has been reported that autophagy is one of the processes contributing to this resistance. In the present study, we found that the anti-cancer drug 5-fluorouraci(5-FU) cou...

Alternative Titles

Full title

Autophagy inhibition promotes 5-fluorouraci-induced apoptosis by stimulating ROS formation in human non-small cell lung cancer A549 cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330882308

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330882308

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0056679

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