Determination of the role of DDX3 a factor involved in mammalian RNAi pathway using an shRNA-express...
Determination of the role of DDX3 a factor involved in mammalian RNAi pathway using an shRNA-expression library
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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RNA interference (RNAi) is an endogenous RNA-destruction phenomenon induced by certain double-stranded RNAs (dsRNAs). In RNAi, dsRNAs are processed into small interfering RNAs (siRNAs) which in turn trigger the cleavage of the target mRNA. Here, using a short hairpin RNA-expression library, we identified a DEAD-box helicase 3, DDX3, as an essential...
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Full title
Determination of the role of DDX3 a factor involved in mammalian RNAi pathway using an shRNA-expression library
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TN_cdi_plos_journals_1330893339
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330893339
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0059445
