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Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippo...

Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330895382

Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice

About this item

Full title

Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-04, Vol.8 (4), p.e60863

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Dehydroepiandrosterone (DHEA) is the most abundant neurosteroid synthesized de novo in the central nervous system. We previously reported that stimulation of the sigma-1 receptor by DHEA improves cognitive function by activating calcium/calmodulin-dependent protein kinase II (CaMKII), protein kinase C and extracellular signal-regulated kinase in th...

Alternative Titles

Full title

Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330895382

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330895382

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0060863

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