Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells
Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Aurora kinase inhibitors are new mitosis-targeting drugs currently in clinical trials for the treatment of haematological and solid malignancies. However, knowledge of the molecular factors that influence sensitivity and resistance remains limited. Herein, we developed and characterised an in vitro leukaemia model of resistance to the Aurora B inhi...
Alternative Titles
Full title
Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells
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TN_cdi_plos_journals_1332847767
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1332847767
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0030734
