Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a m...
Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome
About this item
Full title
Author / Creator
Gribble, Susan M , Wiseman, Frances K , Clayton, Stephen , Prigmore, Elena , Langley, Elizabeth , Yang, Fengtang , Maguire, Sean , Fu, Beiyuan , Rajan, Diana , Sheppard, Olivia , Scott, Carol , Hauser, Heidi , Stephens, Philip J , Stebbings, Lucy A , Ng, Bee Ling , Fitzgerald, Tomas , Quail, Michael A , Banerjee, Ruby , Rothkamm, Kai , Tybulewicz, Victor L J , Fisher, Elizabeth M C and Carter, Nigel P
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Down syndrome (DS) is caused by trisomy of chromosome 21 (Hsa21) and presents a complex phenotype that arises from abnormal dosage of genes on this chromosome. However, the individual dosage-sensitive genes underlying each phenotype remain largely unknown. To help dissect genotype--phenotype correlations in this complex syndrome, the first fully tr...
Alternative Titles
Full title
Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome
Authors, Artists and Contributors
Author / Creator
Wiseman, Frances K
Clayton, Stephen
Prigmore, Elena
Langley, Elizabeth
Yang, Fengtang
Maguire, Sean
Fu, Beiyuan
Rajan, Diana
Sheppard, Olivia
Scott, Carol
Hauser, Heidi
Stephens, Philip J
Stebbings, Lucy A
Ng, Bee Ling
Fitzgerald, Tomas
Quail, Michael A
Banerjee, Ruby
Rothkamm, Kai
Tybulewicz, Victor L J
Fisher, Elizabeth M C
Carter, Nigel P
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1335051361
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1335051361
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0060482
