Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transg...
Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The effects of tau hyperphosphorylation and aggregation on axonal transport were investigated in the optic nerve of mice transgenic for human mutant P301S tau. Transport was examined using cholera toxin B tracing. Retrograde transport was reduced in transgenic mice at 3 and 5 months of age, when compared to C57/Bl6 control mice. Anterograde axonal...
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Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau
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TN_cdi_plos_journals_1340941156
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1340941156
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0034724
