Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miy...
Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro
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Author / Creator
Tanaka, Akihito , Woltjen, Knut , Miyake, Katsuya , Hotta, Akitsu , Ikeya, Makoto , Yamamoto, Takuya , Nishino, Tokiko , Shoji, Emi , Sehara-Fujisawa, Atsuko , Manabe, Yasuko , Fujii, Nobuharu , Hanaoka, Kazunori , Era, Takumi , Yamashita, Satoshi , Isobe, Ken-ichi , Kimura, En and Sakurai, Hidetoshi
Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The establishment of human induced pluripotent stem cells (hiPSCs) has enabled the production of in vitro, patient-specific cell models of human disease. In vitro recreation of disease pathology from patient-derived hiPSCs depends on efficient differentiation protocols producing relevant adult cell types. However, myogenic differentiation of hiPSCs...
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Full title
Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro
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TN_cdi_plos_journals_1346594981
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1346594981
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0061540