A new class of small molecule inhibitor of BMP signaling
A new class of small molecule inhibitor of BMP signaling
About this item
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Growth factor signaling pathways are tightly regulated by phosphorylation and include many important kinase targets of interest for drug discovery. Small molecule inhibitors of the bone morphogenetic protein (BMP) receptor kinase ALK2 (ACVR1) are needed urgently to treat the progressively debilitating musculoskeletal disease fibrodysplasia ossifica...
Alternative Titles
Full title
A new class of small molecule inhibitor of BMP signaling
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TN_cdi_plos_journals_1348122825
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1348122825
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0062721
