Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased p...
Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
The only approved pharmacological treatment for ischemic stroke is intravenous administration of plasminogen activator (tPA) to re-canalize the occluded cerebral vessel. Not only reperfusion but also tPA itself can induce an inflammatory response. Microglia are the innate immune cells of the central nervous system and the first immune cells to beco...
Alternative Titles
Full title
Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation
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TN_cdi_plos_journals_1350377192
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1350377192
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0063118
