Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice
Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Altered autophagy contributes to the pathogenesis of Alzheimer's disease and other tauopathies, for which curative treatment options are still lacking. We have recently shown that trehalose reduces tau pathology in a tauopathy mouse model by stimulation of autophagy. Here, we studied the effect of the autophagy inducing drug rapamycin on the progre...
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Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice
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TN_cdi_plos_journals_1350972580
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1350972580
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0062459
