Nuclear receptor NR4A2 orchestrates Th17 cell-mediated autoimmune inflammation via IL-21 signalling
Nuclear receptor NR4A2 orchestrates Th17 cell-mediated autoimmune inflammation via IL-21 signalling
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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IL-17-producing CD4(+) T helper 17 (Th17) cells are pathogenic in a range of human autoimmune diseases and corresponding animal models. We now demonstrate that such T cells infiltrating the target organ during the induction of experimental autoimmune encephalomyelitis (EAE) and experimental autoimmune uveoretinitis (EAU) specifically express NR4A2....
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Full title
Nuclear receptor NR4A2 orchestrates Th17 cell-mediated autoimmune inflammation via IL-21 signalling
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TN_cdi_plos_journals_1351357837
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1351357837
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0056595
