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HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1

HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1351918629

HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1

About this item

Full title

HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2013-04, Vol.9 (4), p.e1003248-e1003248

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Upon recognition of viral components by pattern recognition receptors, such as the toll-like receptors (TLRs) and retinoic acid-inducible gene I (RIG-I)-like helicases, cells are activated to produce type I interferon (IFN) and proinflammatory cytokines. These pathways are tightly regulated by the host to prevent an inappropriate cellular response,...

Alternative Titles

Full title

HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1351918629

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1351918629

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1003248

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