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Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficit...

Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1371831025

Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease

About this item

Full title

Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-06, Vol.8 (6), p.e68062-e68062

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

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Scope and Contents

Contents

Prion diseases are fatal neurodegenerative diseases of the CNS that are associated with the accumulation of misfolded cellular prion protein. There are several different strains of prion disease defined by different patterns of tissue vacuolation in the brain and disease time course, but features of neurodegeneration in these strains have not been...

Alternative Titles

Full title

Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1371831025

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1371831025

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0068062

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