Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficit...
Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Prion diseases are fatal neurodegenerative diseases of the CNS that are associated with the accumulation of misfolded cellular prion protein. There are several different strains of prion disease defined by different patterns of tissue vacuolation in the brain and disease time course, but features of neurodegeneration in these strains have not been...
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Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease
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TN_cdi_plos_journals_1371831025
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1371831025
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0068062