Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells
Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Sound detection by inner ear hair cells requires tip links that interconnect mechanosensory stereocilia and convey force to yet unidentified transduction channels. Current models postulate a static composition of the tip link, with protocadherin 15 (PCDH15) at the lower and cadherin 23 (CDH23) at the upper end of the link. In terminally differentia...
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Full title
Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells
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TN_cdi_plos_journals_1427353533
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1427353533
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1001583
